"Run for office? No. I've slept with too many women, I've done too many drugs, and I've been to too many parties"

In this quote, George Clooney is expressing his unwillingness to run for political workplace. He lists three factors for this: his previous sexual encounters with multiple ladies, his history of drug use, and his attendance at various parties. By mentioning these things, Clooney is acknowledging that they might be seen as questionable or scandalous by the public and might possibly damage his chances of being chosen. He is also suggesting that these experiences have formed him into the individual he is today and he is not ready to jeopardize or conceal them in order to pursue a political career. In general, Clooney is making a declaration about the expectations and standards put on political leaders and how his personal choices might not align with them.